Stir together vodka, orange liqueur, Cranberry Reduction, and fresh lemon juice in a cocktail shaker filled with ice cubes. Cover with lid, and shake vigorously until thoroughly chilled (about 30 seconds).
Strain mixture into a chilled coupe or martini glass. Garnish, if desired.
In a blender, whirl the mango; 3/4 cup plain low-fat yogurt; 2 tablespoons honey; the fresh lime juice; 2 ice cubes; and the freshly grated lime zest until smooth. Divide mango-lime smoothie between 2 straight-sided glasses and set aside.
Rinse blender, then whirl the banana; the strawberries; 1/2 cup plain low-fat yogurt; 2 tablespoons honey; the fresh lemon juice; 2 ice cubes; and the freshly grated lemon zest until smooth.
Layer banana-strawberry smoothie onto mango smoothie, gently spooning mixture around inside edge of each glass to create a clean horizontal line.